CD44 anticorps

N° du produit ABIN1449180

Cet anticorps anti-CD44 est un anticorps Souris Monoclonal détectant CD44 dans FACS et IP. Adapté pour Humain.

Aperçu rapide pour CD44 anticorps (ABIN1449180)

Antigène: CD44

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD44 est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: 15C6

Détail du produit anti-CD44 anticorps

Specificité: This antibody reacts with CD44 antigen.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Protein A agarose

Immunogène: MML-1 human leukemia cells

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 50 % glycerol, pH 7.2. No preservative is contained.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD44

Antigène: CD44

Autre désignation: CD44

Sujet: CD44 (H-CAM/Pgp-1/Hermes antigen/ECMR-III/HUTCH-I) is a highly glycosylated transmembrane protein expressed by lymphocytes, fibroblasts, smooth muscle cells, and epithelial cells. CD44 functions as lymphocyte adhesion molecule, acting as a matrix receptor that mediates cell adhesion to the extracellular matrix. CD44 is also involved in T-lymphocyte activation, lymphocyte homing, cell migration, and hemopoiesis. Expression of CD44 on the cell surface changes profoundly during tumor metastasis, and the transition from non-metastatic to metastatic tumor cell variants is associated with expression of CD44 variants (CD44v's), making CD44 a potential cancer marker. CD44 has a predicted molecular weight of 85-90 kDa, but glycosylation can increase the apparent to ~200 kDa.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

ID gène: 960

NCBI Accession: NP_000601

UniProt: P16070

Pathways: Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling